Surgical Sealant
AQUABRID®
AQUABRID® is a fully synthetic surgical sealant for aortic surgical procedures. Ideal for wet conditions.
Developed for Wet Conditions
AQUABRID® is a fully synthetic surgical sealant for aortic surgical procedures.
In contact with water AQUABRID® forms an elastic layer within 3 to 5 minutes – making it optimal for use on wet conditions.1, 2
AQUABRID® stretches and shrinks with contraction of the vessel, while maintaining a strong seal in the aorta.1, 2
AQUABRID® has been commercially available in Japan since 2014 under the name of HYDROFIT®.
How does AQUABRID® work?
AQUABRID® can be applied to natural and/or artificial tissue (e.g. aortic graft). The surgical site does not need to be dry, AQUABRID® requires blood/moisture for reaction.
Suture
Moisture/Blood
Lumen
Tissue/Graft
A thin layer of AQUABRID® (liquid) is applied to seal the suture holes.
AQUABRID® absorbs the moisture/blood and doubles it’s regional volume.
AQUABRID® forms an elastic film after polymerization with CO2 release.
This curing process takes 3-5 mins. 1, 2
Ideal to Support each Aortic Anastomosis?
Due to it‘s hydrophilic properties AQUABRID® can be applied to the aortic anastomosis immediately. It stretches and shrinks with the vessel contractions while maintaining a strong seal.1, 2
Benefits of AQUABRID®
Reacts with water 1, 2
Optimal use for wet surfaces, regardless of heparinisation conditions
Strong 1, 2
Maintains bond/seal in the high pressure environment of the aorta
Elastic 1, 2, 4
Stretches and shrinks with the vessel contractions
Ready to use 4
No manual mixing or preparation required
100 % synthetic 2, 4
No biological origin or risk of infection
Application of AQUABRID®
Only a thin layer of AQUABRID® is required. The sealant is cured after 3-5 mins 1, 2
Direct Method
Apply AQUABRID® directly from the syringe to the bleeding spot
Place or wrap the silicone sheet around the vessel
(if needed)
Transfer method
Spread AQUABRID® onto the included silicone sheet for areas hard to reach
Place or wrap the silicone sheet on the bleeding spot
References
Eto M et al Elastomeric surgical sealant for hemostasis of cardiovascular anastomosis under full heparinization. Europ. J. Cardio Surg. 2007; 730-734.
Oda S. et al. Experimental use of an elastomeric surgical sealant for arterial hemostasis and its long-term tissue response. Interac. Cardiov. and Thor. Surgery. 2010; 258-261.
Matsuoka, Tadashi et al “A surgical sealant, AQUABRID decreased the volume of intraoperative blood transfusions and operative time for acute aortic dissection repair.” Journal of Cardiac Surgery. Vol. 37,12 (2022): 5073-5080. doi:10.1111/jocs.17208
AQUABRID® Instruction for use.
Product Disclaimer
Product availability subject to local regulatory approval.
HYDROFIT® & AQUABRID® are registered trademarks of Sanyo Chemical Industries, Ltd.
An EU Declaration of Conformity may be requested from regulatoryaffairsuk@terumoaortic.com
Instructions for Use
An IFU is supplied with all AQUABRID® products.
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