Aquabrid®
Strong and Elastic, Ideal for Wet Conditions.
AQUABRID® is a fully synthetic surgical sealant for aortic surgical procedures.
Developed for Wet Conditions
AQUABRID® is a fully synthetic surgical sealant for aortic surgical procedures.
In contact with water, it forms an elastic layer within 3 to 5 minutes – making it optimal for use on wet conditions.1, 2
It stretches and shrinks with contraction of the vessel, while maintaining a strong seal in the aorta.1, 2
It has been commercially available in Japan since 2014 under the name of HYDROFIT®.
How does it work?
It can be applied to natural and/or artificial tissue (e.g. aortic graft). The surgical site does not need to be dry, it requires blood/moisture for reaction.
Lumen
Suture
Moisture/Blood
Tissue/Graft
Step 1
A thin layer of AQUABRID® (liquid) is applied to seal the suture holes.
It absorbs the moisture/blood and doubles it’s regional volume..
It forms an elastic film after polymerization with CO2 release.
This curing process takes 3-5 mins. 1, 2
Ideal to Support each Aortic Anastomosis
Due to it‘s hydrophilic properties, it can be applied to the aortic anastomosis immediately. It stretches and shrinks with the vessel contractions while maintaining a strong seal.1, 2
Reduction in time associated with bleeding control 3
Reduction in number of blood transfusions 3
Benefits
Reacts with water 1, 2
Optimal use for wet surfaces, regardless of heparinisation conditions
Strong 1, 2
Maintains bond/seal in the high pressure environment of the aorta
Elastic 1, 2, 4
Stretches and shrinks with the vessel contractions
Ready to use 4
No manual mixing or preparation required
100 % synthetic 2, 4
No biological origin or risk of infection
Application
Only a thin layer is required. The sealant is cured after 3-5 mins 1, 2
Direct Method
Apply directly from the syringe to the bleeding spot
Place or wrap the silicone sheet around the vessel
(if needed)
Transfer method
Spread onto the included silicone sheet for areas hard to reach
Place or wrap the silicone sheet on the bleeding spot
References
Eto M et al Elastomeric surgical sealant for hemostasis of cardiovascular anastomosis under full heparinization. Europ. J. Cardio Surg. 2007; 730-734.
Oda S. et al. Experimental use of an elastomeric surgical sealant for arterial hemostasis and its long-term tissue response. Interac. Cardiov. and Thor. Surgery. 2010; 258-261.
Matsuoka, Tadashi et al “A surgical sealant, AQUABRID® decreased the volume of intraoperative blood transfusions and operative time for acute aortic dissection repair.” Journal of Cardiac Surgery. Vol. 37,12 (2022): 5073-5080. doi:10.1111/jocs.17208
AQUABRID® Instruction for use.
Product Disclaimer
Product availability subject to local regulatory approval.
HYDROFIT® & AQUABRID® are registered trademarks of Sanyo Chemical Industries, Ltd.
An EU Declaration of Conformity may be requested from regulatoryaffairsuk@terumoaortic.com
Instructions for Use
An IFU is supplied with all AQUABRID® products.
